Flow cytometry characterization data are now available for thirteen immunodeficient JAX strains (000819, 002019, 007850, 001913, 001803, 001131, 001303, 005557, 013062, 007799, 002216, 003145, 001011). The levels of B cells, T cells (CD8 and CD4), and NK cells were measured in whole blood and spleen preparations.
Figure 1 Representative flow cytometry scatter plot showing the absence of CD19-positive B cells and CD3e-positive T cells in the peripheral blood of immunodeficient NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (“NSG”; 005557) female mice compared to the wildtype control strain, NOD/ShiLtJ (001976).