The Mouse Mutant Resource
The Mouse Mutant Resource (MMR) is the primary repository at The Jackson Laboratory of strains and stocks carrying spontaneous genetic mutations. The MMR performs three vital functions:
* Characterization of new spontaneous mutations in mice that occur within the large breeding colonies of The Jackson Laboratory
* Maintenance and distribution of established mutant stocks
* Preservation of spontaneous mutation stocks
Approximately 270 established mutant stocks are maintained in the MMR and 60-70 new mutations are at various stages of characterization. New mutant mice are made available to the scientific community once they have been characterized and described in journal publications or on this web site.
Stock Availability Information. MMR stocks are included in the Jax Mice Catalogue and on-line at the JAX Mice web site, which can be searched by gene name, strain name, stock number, strain type, or research area. Mice from MMR stocks are available as breeding pairs or in small numbers (JAX Mice Level 4). Stocks that are temporarily not in demand are discontinued as breeding colonies. Most stocks are cryopreserved as embryos prior to their removal from the breeding colony. DNA is always preserved from all stocks.
Funding Sources. The MMR is supported by a National Institutes of Health grant, TJL institutional funds, and fees from the sale and distribution of mice. Primary MMR support comes from NIH-NCRR grant RR01183 . In publications on mice from the MMR, please cite the MMR and this grant for providing the mice.
